Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Yap1  yes-associated protein 1   (Synonyms: Yap, Yki, yorkie)
Results	Reference
1*	J:236337 Abbassi L, Malki S, Cockburn K, Macaulay A, Robert C, Rossant J, Clarke HJ, Multiple Mechanisms Cooperate to Constitutively Exclude the Transcriptional Co-Activator YAP from the Nucleus During Murine Oogenesis. Biol Reprod. 2016 May;94(5):102
1	J:331266 Abou Nader N, Menard A, Levasseur A, St-Jean G, Boerboom D, Zamberlam G, Boyer A, Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate. Int J Mol Sci. 2022 Nov 5;23(21)
1	J:264380 Artap S, Manderfield LJ, Smith CL, Poleshko A, Aghajanian H, See K, Li L, Jain R, Epstein JA, Endocardial Hippo signaling regulates myocardial growth and cardiogenesis. Dev Biol. 2018 Aug 1;440(1):22-30
1	J:226938 Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA, Blencowe BJ, Helmbacher F, McNeill H, Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. Development. 2015 Aug 1;142(15):2564-73
1	J:301556 Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS, YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 Dec 13;147(23):dev195453
1	J:245870 Cotton JL, Li Q, Ma L, Park JS, Wang J, Ou J, Zhu LJ, Ip YT, Johnson RL, Mao J, YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme. Dev Cell. 2017 Oct 09;43(1):35-47.e4
1	J:201586 Das A, Tanigawa S, Karner CM, Xin M, Lum L, Chen C, Olson EN, Perantoni AO, Carroll TJ, Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. Nat Cell Biol. 2013 Sep;15(9):1035-44
1	J:290788 Gnedeva K, Wang X, McGovern MM, Barton M, Tao L, Trecek T, Monroe TO, Llamas J, Makmura W, Martin JF, Groves AK, Warchol M, Segil N, Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13552-13561
1	J:333075 Goodwin AF, Chen CP, Vo NT, Bush JO, Klein OD, YAP/TAZ Regulate Elevation and Bone Formation of the Mouse Secondary Palate. J Dent Res. 2020 Nov;99(12):1387-1396
1*	J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162
1*	J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347
1	J:288374 Kostic M, Paridaen JTML, Long KR, Kalebic N, Langen B, Grubling N, Wimberger P, Kawasaki H, Namba T, Huttner WB, YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex. Cell Rep. 2019 Apr 23;27(4):1103-1118.e6
1*	J:309394 Kwon HJ, Li L, Jung HS, Hippo pathway/Yap regulates primary enamel knot and dental cusp patterning in tooth morphogenesis. Cell Tissue Res. 2015 Nov;362(2):447-51
1	J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93
1	J:240835 Li CY, Hu J, Lu H, Lan J, Du W, Galicia N, Klein OD, alphaE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development. Nat Commun. 2016 Jul 13;7:12133
1*	J:170274 Li L, Kwon HJ, Harada H, Ohshima H, Cho SW, Jung HS, Expression patterns of ABCG2, Bmi-1, Oct-3/4, and Yap in the developing mouse incisor. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):163-70
1	J:190509 Li Y, Hibbs MA, Gard AL, Shylo NA, Yun K, Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1. Stem Cells. 2012 Apr;30(4):741-52
1	J:244106 Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson-Peer K, Chuang PT, YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. Elife. 2017 Mar 21;6:e21130
1	J:267913 Liu WA, Chen S, Li Z, Lee CH, Mirzaa G, Dobyns WB, Ross ME, Zhang J, Shi SH, PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev. 2018 Jun 1;32(11-12):763-780
1	J:274694 Lodge EJ, Santambrogio A, Russell JP, Xekouki P, Jacques TS, Johnson RL, Thavaraj S, Bornstein SR, Andoniadou CL, Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade. Elife. 2019 Mar 26;8:e43996
1	J:306379 Mohad V, Lungova V, Verheyden J, Thibeault SL, Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis. Dev Biol. 2021 May;473:33-49
1	J:241275 Reginensi A, Enderle L, Gregorieff A, Johnson RL, Wrana JL, McNeill H, A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016 Aug 02;7:12309
1	J:286313 Shea CA, Rolfe RA, McNeill H, Murphy P, Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation. Dev Dyn. 2020 Apr;249(4):523-542
1	J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90
1	J:239794 Szymaniak AD, Mahoney JE, Cardoso WV, Varelas X, Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap. Dev Cell. 2015 Aug 10;34(3):283-96
1	J:256856 Szymaniak AD, Mi R, McCarthy SE, Gower AC, Reynolds TL, Mingueneau M, Kukuruzinska M, Varelas X, The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland. Elife. 2017 May 11;6:e23499
1	J:290308 van Soldt BJ, Qian J, Li J, Tang N, Lu J, Cardoso WV, Yap and its subcellular localization have distinct compartment-specific roles in the developing lung. Development. 2019 May 1;146(9):dev175810
1	J:272593 Volckaert T, Yuan T, Yuan J, Boateng E, Hopkins S, Zhang JS, Thannickal VJ, Fassler R, De Langhe SP, Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and beta-catenin signaling. Development. 2019 Jan 16;146(2):dev166454
1	J:342339 Xia M, Wu M, Li Y, Liu Y, Jia G, Lou Y, Ma J, Gao Q, Xie M, Chen Y, He Y, Li H, Li W, Varying mechanical forces drive sensory epithelium formation. Sci Adv. 2023 Nov 3;9(44):eadf2664
1	J:317198 Yang Y, Paivinen P, Xie C, Krup AL, Makela TP, Mostov KE, Reiter JF, Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation. Nat Commun. 2021 Dec 10;12(1):7186
1	J:259567 Zhang D, Yang S, Toledo EM, Gyllborg D, Salto C, Carlos Villaescusa J, Arenas E, Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP. Sci Signal. 2017 Aug 22;10(493)